Title : Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium.

Pub. Date : 2008 Jun

PMID : 18375743






1 Functional Relationships(s)
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1 We conclude that multiple TLR ligands induce airway epithelial cell production of IL-8 and VEGF via a Duox1--> ROS--> TACE--> TGF-alpha--> EGFR phosphorylation pathway. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens