Title : Bortezomib (Velcadetrade mark) in the Treatment of Multiple Myeloma.

Pub. Date : 2006 Sep

PMID : 18360602






2 Functional Relationships(s)
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1 In pre-clinical studies bortezomib showed a number of different anti-myeloma effects including disruption of the cell cycle and induction of apoptosis, alteration of the bone marrow microenvironment and inhibition of nuclear factor kappa B (NFkappaB). Bortezomib nuclear factor kappa B subunit 1 Homo sapiens
2 In pre-clinical studies bortezomib showed a number of different anti-myeloma effects including disruption of the cell cycle and induction of apoptosis, alteration of the bone marrow microenvironment and inhibition of nuclear factor kappa B (NFkappaB). Bortezomib nuclear factor kappa B subunit 1 Homo sapiens