Title : Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone.

Pub. Date : 2008 Mar 14

PMID : 18341691






2 Functional Relationships(s)
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1 Using the electrophoretic mobility shift assays, we determined the binding of nuclear proteins to oligonucleotides encoding the putative cd38 NF-kappaB, AP-1, and GRE sites, and the specificity of this binding was confirmed by gel supershift analysis with appropriate antibodies. Oligonucleotides nuclear factor kappa B subunit 1 Homo sapiens
2 The binding of nuclear proteins to oligonucleotides encoding the putative cd38 NF-kappaB site and some of the six AP-1 sites was increased by TNF-alpha, and to some of the putative cd38 GREs by dexamethasone. Oligonucleotides nuclear factor kappa B subunit 1 Homo sapiens