Title : Discodermolide--a new, marine-derived immunosuppressive compound. I. In vitro studies.

Pub. Date : 1991 Oct

PMID : 1833864






1 Functional Relationships(s)
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1 The production of IL-2 by PMA-ionomycin stimulated T cells was not inhibited by discodermolide; however, the percentage of IL-2 receptor-bearing cells as measured by immunofluorescence with 7D4 antibody, specific for the 55-kDa chain (p55) comprising the murine IL-2 receptor, was reduced. Tetradecanoylphorbol Acetate interleukin 2 Mus musculus