Pub. Date : 1991 Aug 15
PMID : 1831195
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Tyrosine phosphorylation of proteins was examined in NIH3T3 cells transformed by an oncogenic form of the trk protein. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |
2 | Proteins of 148, 140, 70, and 55 kDa were phosphorylated on tyrosine residues in trk-transformed cells but not control NIH3T3 cells. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |
3 | The 70-kDa protein may represent the trk oncogene protein itself which was shown to be tyrosine-phosphorylated in vivo using trk-specific antiserum. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |
4 | The 70-kDa protein may represent the trk oncogene protein itself which was shown to be tyrosine-phosphorylated in vivo using trk-specific antiserum. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |
5 | Phospholipase C-gamma 1 (PLC-gamma 1) was also found to be constitutively tyrosine-phosphorylated in trk-transformed cells and the trk protein co-immunoprecipitated with PLC-gamma. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |
6 | Phospholipase C-gamma 1 (PLC-gamma 1) was also found to be constitutively tyrosine-phosphorylated in trk-transformed cells and the trk protein co-immunoprecipitated with PLC-gamma. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |
7 | The GTPase-activating protein of ras (GAP) and the 62-kDa GAP-associated protein were tyrosine-phosphorylated in trk-transformed cells, and a lesser amount of trk co-immunoprecipitated with GAP relative to with PLC-gamma. | Tyrosine | neurotrophic tyrosine kinase, receptor, type 1 | Mus musculus |