Title : Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.

Pub. Date : 2008 May

PMID : 18305093






1 Functional Relationships(s)
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1 Obese rats had significantly greater net natriuretic response to single injections of hydrochlorothiazide and benzamil, suggesting increased activity of NCC and ENaC, respectively; however, only the response to benzamil was reduced by CAN. Hydrochlorothiazide sodium channel epithelial 1 subunit gamma Rattus norvegicus