Title : Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes.

Pub. Date : 2008 May

PMID : 18293408






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NFATs are activated by calcium-mobilizing agents in astrocytes, and this activation is blocked by the calcineurin inhibitor cyclosporine A. Calcium calcineurin binding protein 1 Homo sapiens
2 Microarray screening identified cyclooxygenase-2 (Cox-2), which is implicated in brain injury, and Rcan 1-4, an endogenous calcineurin inhibitor, as genes up-regulated by calcineurin-dependent calcium signals in astrocytes. Calcium calcineurin binding protein 1 Homo sapiens