Title : Effects of apicidin, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells.

Pub. Date : 2008 Mar

PMID : 18288380






2 Functional Relationships(s)
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Protein Name
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1 Studies on the regulation of apoptosis showed that apicidin induces the up-regulation of p53 and the downstream activation of ERK in MCF10A-ras cells. apicidin mitogen-activated protein kinase 1 Homo sapiens
2 Therefore, the apicidin-mediated ERK pathway appears to play an important role in modulating the pro-apoptotic pathway in MCF10A-ras cells. apicidin mitogen-activated protein kinase 1 Homo sapiens