Title : In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation.

Pub. Date : 2008 Mar

PMID : 18258818






3 Functional Relationships(s)
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1 To investigate whether increased endothelial cell expression of lipoprotein lipase (LpL), the primary enzyme creating free fatty acids from circulating triglycerides (TG), affects vascular function, we created transgenic mice that express human LpL (hLpL) driven by the promoter and enhancer of the Tie2 receptor. Triglycerides lipoprotein lipase Mus musculus
2 To investigate whether increased endothelial cell expression of lipoprotein lipase (LpL), the primary enzyme creating free fatty acids from circulating triglycerides (TG), affects vascular function, we created transgenic mice that express human LpL (hLpL) driven by the promoter and enhancer of the Tie2 receptor. Triglycerides lipoprotein lipase Mus musculus
3 To investigate whether increased endothelial cell expression of lipoprotein lipase (LpL), the primary enzyme creating free fatty acids from circulating triglycerides (TG), affects vascular function, we created transgenic mice that express human LpL (hLpL) driven by the promoter and enhancer of the Tie2 receptor. Triglycerides lipoprotein lipase Mus musculus