Title : D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways.

Pub. Date : 2008 Mar 5

PMID : 18242171






2 Functional Relationships(s)
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1 D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways. Rotenone mitogen-activated protein kinase 8 Homo sapiens
2 We found that ropinirole can block the rotenone-induced phosphorylation of JNK, P38 and p-c-Jun, but promote the phosphorylation of ERK1/2. Rotenone mitogen-activated protein kinase 8 Homo sapiens