Title : Specificity of stimulation of human 8-oxoguanine-DNA glycosylase by AP endonuclease.

Pub. Date : 2008 Mar 28

PMID : 18222119






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we report that APEX1 efficiently stimulates OGG1 on good substrates (8-oxoadenine, 8-oxoinosine, or 6-methoxy-8-oxoguanine opposite to cytosine) but the stimulation is low or absent with poor OGG1 substrates (8-oxoadenine or 8-oxoinosine opposite to thymine; 8-oxoG or 8-aminoguanine opposite to adenine; 8-oxonebularine, 8-metoxyguanine, inosine or guanine opposite to cytosine). Guanine 8-oxoguanine DNA glycosylase Homo sapiens