Title : Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids.

Pub. Date : 2008 Mar

PMID : 18219447






2 Functional Relationships(s)
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1 Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids. Progesterone brain-derived neurotrophic factor Rattus norvegicus
2 Progesterone pretreatment enhanced the stimulatory action of serotonin on BDNF gene expression, and the enhancement of serotonin action observed in the cells pretreated with progesterone was almost completely abolished by finasteride, an inhibitor of the enzyme involved in the production of 5alpha-reduced neurosteroids. Progesterone brain-derived neurotrophic factor Rattus norvegicus