Title : Regulation of adaptor protein GIT1 in platelets, leading to the interaction between GIT1 and integrin alpha(IIb)beta3.

Pub. Date : 2008 Mar 28

PMID : 18211801






1 Functional Relationships(s)
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1 These results suggest that tyrosine phosphorylation of GIT1 by Src kinases may regulate cytoskeletal reorganization downstream of alpha(IIb)beta(3) by bringing the Rac GEF betaPIX to the vicinity of the integrin. Tyrosine Ras protein specific guanine nucleotide releasing factor 1 Homo sapiens