Title : Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.

Pub. Date : 2008 Feb

PMID : 18211286






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This FASN-triggered HER1/HER2-breast cancer-like phenotype was specifically inhibitable either by FASN inhibitor C75 or by Tyr-kinase inhibitors (TKIs) gefitinib (Iressa) and lapatinib (Tykerb) but not by chemotherapeutic agents such as cisplatin. Cisplatin epidermal growth factor receptor Homo sapiens