Title : Role of sunitinib and sorafenib in the treatment of metastatic renal cell carcinoma.

Pub. Date : 2008 Jan 15

PMID : 18192256






1 Functional Relationships(s)
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1 Sorafenib inhibits VEGF receptors, PDGF receptors, FLT3, RAF-1, and BRAF in vitro and has been shown to prevent the growth of tumors but not to reduce tumor size. Sorafenib B-Raf proto-oncogene, serine/threonine kinase Homo sapiens