Title : Edaravone prevents Fas-induced fulminant hepatic failure in mice by regulating mitochondrial Bcl-xL and Bax.

Pub. Date : 2008 Aug

PMID : 18180697






3 Functional Relationships(s)
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1 Edaravone prevents Fas-induced fulminant hepatic failure in mice by regulating mitochondrial Bcl-xL and Bax. Edaravone BCL2-like 1 Mus musculus
2 Western blotting showed that the Bcl-xL-Bax ratio of the edaravone group was much higher than that of the control group. Edaravone BCL2-like 1 Mus musculus
3 In conclusion, edaravone might protect hepatocytes from Fas-induced mitochondria-dependent apoptosis by regulating mitochondrial Bcl-xL and Bax. Edaravone BCL2-like 1 Mus musculus