Title : Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophages.

Pub. Date : 2008 Jan 15

PMID : 18178819






2 Functional Relationships(s)
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1 Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophages. CPG-oligonucleotide interleukin 10 Mus musculus
2 We show in this study that peritoneal macrophages from SCID mice having mutations in the catalytic subunit of DNA-protein kinase (DNA-PKcs) were almost completely defective in the production of IL-10 and in ERK activation when treated with CpG-ODN. CPG-oligonucleotide interleukin 10 Mus musculus