Title : Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide.

Pub. Date : 2008 Mar

PMID : 18178725






2 Functional Relationships(s)
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Protein Name
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1 Induction of HO-1 was associated with an attenuation of pulmonary arterial relaxation to the NO-donor spermine-NONOate. spermine nitric oxide complex heme oxygenase 1 Homo sapiens
2 However, the increase in activity seen in the presence of 1 microM spermine-NONOate was attenuated in homogenates obtained from arteries with increased HO-1. spermine nitric oxide complex heme oxygenase 1 Homo sapiens