Pub. Date : 2008 Jan
PMID : 18173748
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Defining the function of beta-catenin tyrosine phosphorylation in cadherin-mediated cell-cell adhesion. | Tyrosine | catenin beta 1 | Homo sapiens |
| 2 | Beta-catenin is a key protein in cadherin-catenin cell adhesion complex and its tyrosine phosphorylation is believed to cause destruction of junctional apparatus. | Tyrosine | catenin beta 1 | Homo sapiens |
| 3 | To directly evaluate the effect of beta-catenin tyrosine phosphorylation in cell adhesion, we utilized F9 cells in which expression of endogenous beta-catenin and its closely related protein plakoglobin were completely shut down. | Tyrosine | catenin beta 1 | Homo sapiens |
| 4 | We show that beta-catenin with phosphorylation mutation at 654th tyrosine forms functional cadherin-catenin complex to mediate strong cadherin-mediated cell adhesion. | Tyrosine | catenin beta 1 | Homo sapiens |
| 5 | We also demonstrate that tyrosine phosphorylation of beta-catenin might regulate cadherin-mediated cell adhesion in a more complicated way than previously expected. | Tyrosine | catenin beta 1 | Homo sapiens |