Title : UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells.

Pub. Date : 2008 Jan 2

PMID : 18167556






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the present studies we hypothesize an opposing effect of glucose on the regulation of UCP-2 and UCP-3 in pancreatic islets. Glucose uncoupling protein 3 Homo sapiens
2 UCP-3 overexpression improved glucose-stimulated insulin secretion. Glucose uncoupling protein 3 Homo sapiens
3 Increased expression of UCP-2 and decreased expression of UCP-3 in humans with chronic hyperglycemia may contribute to impaired glucose-stimulated insulin secretion. Glucose uncoupling protein 3 Homo sapiens