Title : Derlin-1 facilitates the retro-translocation of cholera toxin.

Pub. Date : 2008 Mar

PMID : 18094046






1 Functional Relationships(s)
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1 These findings indicate that Derlin-1 facilitates the retro-translocation of CT. CTB may play a role in this process by targeting the holotoxin to Derlin-1, enabling the Derlin-1-bound PDI to unfold the A1 subunit and prepare it for transport. stichoposide prolyl 4-hydroxylase subunit beta Homo sapiens