Title : 15-Lipoxygenase-2 is differentially expressed in normal and neoplastic ovary.

Pub. Date : 2007 Dec

PMID : 18090132






1 Functional Relationships(s)
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1 For this study, we quantified the expression of eicosanoid-related enzymes (cyclooxygenase-1 and cyclooxygenase-2, 15-lipoxygenase-1 and lipoxygenase-2, 5-lipoxygenase) in normal and malignant human ovarian tissue by real-time polymerase chain reaction and found a 22-fold elevated expression of 15-lipoxygenase-2 in malignant specimens when compared with normal ovarian tissue (P=0.001). Eicosanoids prostaglandin-endoperoxide synthase 1 Homo sapiens