Title : Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages.

Pub. Date : 2008 Feb

PMID : 18082129






1 Functional Relationships(s)
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1 These findings extend our understanding of the homeostatic function of UCP2 in regulating mitochondrial reactive oxygen production by identifying a feedback loop that senses mitochondrial reactive oxygen production and increases inner mitochondrial membrane UCP2 abundance and activity. reactive oxygen uncoupling protein 2 Homo sapiens