Pub. Date : 2007 Dec
PMID : 18068629
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 2 | Here, we show that loss of the ECM protein TGFBI (transforming growth factor beta induced) is sufficient to induce specific resistance to paclitaxel and mitotic spindle abnormalities in ovarian cancer cells. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 3 | Here, we show that loss of the ECM protein TGFBI (transforming growth factor beta induced) is sufficient to induce specific resistance to paclitaxel and mitotic spindle abnormalities in ovarian cancer cells. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 4 | Paclitaxel-resistant cells treated with recombinant TGFBI protein show integrin-dependent restoration of paclitaxel sensitivity via FAK- and Rho-dependent stabilization of microtubules. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 5 | Paclitaxel-resistant cells treated with recombinant TGFBI protein show integrin-dependent restoration of paclitaxel sensitivity via FAK- and Rho-dependent stabilization of microtubules. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 6 | Immunohistochemical staining for TGFBI in paclitaxel-treated ovarian cancers from a prospective clinical trial showed that morphological changes of paclitaxel-induced cytotoxicity were restricted to areas of strong expression of TGFBI. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 7 | Immunohistochemical staining for TGFBI in paclitaxel-treated ovarian cancers from a prospective clinical trial showed that morphological changes of paclitaxel-induced cytotoxicity were restricted to areas of strong expression of TGFBI. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |
| 8 | Immunohistochemical staining for TGFBI in paclitaxel-treated ovarian cancers from a prospective clinical trial showed that morphological changes of paclitaxel-induced cytotoxicity were restricted to areas of strong expression of TGFBI. | Paclitaxel | transforming growth factor beta induced | Homo sapiens |