Pub. Date : 2007 Dec
PMID : 18049993
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acrylamide is neurotoxic and is metabolized by cytochrome P-450 (CYP) 2E1 to a mutagenic epoxide, glycidamide. | Acrylamide | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |
| 2 | Early life immaturities tended to exert a greater effect on acrylamide than glycidamide dosimetry because immaturities in CYP2E1 and glutathione counteract one another for glycidamide AUC, but both lead to greater acrylamide dose. | Acrylamide | cytochrome P450 family 2 subfamily E member 1 | Homo sapiens |