Title : Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide.

Pub. Date : 2008 Apr

PMID : 18047562






1 Functional Relationships(s)
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1 We evaluated TH positive neurons, astroglial, and microglial populations and found that simvastatin prevented the inflammatory processes, as the induction of interleukin-1beta, tumor necrosis factor-alpha, and iNOS and the consequent dopaminergic degeneration induced by LPS. Simvastatin nitric oxide synthase 2 Rattus norvegicus