Title : Neurokinin-1 receptor antagonist (aprepitant) inhibits drug-resistant HIV-1 infection of macrophages in vitro.

Pub. Date : 2007 Mar

PMID : 18040825






1 Functional Relationships(s)
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1 We have previously shown that CP-96,345, a neurokinin-1 receptor (NK-1R) antagonist, inhibits HIV-1 infection of macrophages in vitro by downregulating CCR5 expression (Lai JP, Ho WZ, Zhan GX, Yi Y, Collman RG, Douglas SD 2001). CP96 C-C motif chemokine receptor 5 Homo sapiens