Title : Folylpolyglutamate synthase and gamma-glutamyl hydrolase regulate leucovorin-enhanced 5-fluorouracil anticancer activity.

Pub. Date : 2008 Jan 25

PMID : 18035049






2 Functional Relationships(s)
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1 Folylpolyglutamate synthase and gamma-glutamyl hydrolase regulate leucovorin-enhanced 5-fluorouracil anticancer activity. Fluorouracil folylpolyglutamate synthase Homo sapiens
2 These results suggest that FPGS and GGH expression levels in tumors are determinants of the efficacy of LV in enhancing the antitumor activity of 5-FU. Fluorouracil folylpolyglutamate synthase Homo sapiens