Pub. Date : 2007 Nov
PMID : 18025275
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FPGS modulation-induced changes in polyglutamylation of both antifolates and folate cofactors and in intracellular folate pools affected chemosensitivity of breast cancer cells to pemetrexed and trimetrexate whose cytotoxic effects do or do not depend on polyglutamylation, respectively, in a predictable manner. | Trimetrexate | folylpolyglutamate synthase | Homo sapiens |