Title : Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.

Pub. Date : 2008 Jan 18

PMID : 18023967






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells. plumbagin mitogen-activated protein kinase 8 Homo sapiens
2 Moreover, blocking ERK and JNK by specific inhibitors suppressed plumbagin-triggered mitochondrial apoptotic pathway. plumbagin mitogen-activated protein kinase 8 Homo sapiens