Pub. Date : 2007 Aug 21
PMID : 18019535
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold. | pyridine | coagulation factor II, thrombin | Homo sapiens |
2 | A Grignard exchange reaction was used to introduce various benzoyl substituents in position 4 of the pyridine ring, where they serve as P3 residues in binding to thrombin. | pyridine | coagulation factor II, thrombin | Homo sapiens |