Title : Chemical genetic screening identifies tricyclic compounds that decrease cellular melanin content.

Pub. Date : 2008 May

PMID : 18007583






3 Functional Relationships(s)
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Protein Name
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1 Immunofluorescence localization revealed that these compounds decreased intracellular melanin content by disrupting the intracellular trafficking of Tyr gene family proteins. Melanins tyrosinase Mus musculus
2 Our results show that these compounds decreased intracellular melanin content by altering the trafficking of Tyr gene family proteins and inducing abnormal secretion of Tyr. Melanins tyrosinase Mus musculus
3 Our results show that these compounds decreased intracellular melanin content by altering the trafficking of Tyr gene family proteins and inducing abnormal secretion of Tyr. Melanins tyrosinase Mus musculus