Pub. Date : 2008 Apr
PMID : 18006877
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In a cell-free system, acrolein increased pro-hMMP9 cleavage and activity in concentrations (100-300 nM) found in sputum from subjects with COPD. | Acrolein | matrix metallopeptidase 9 | Homo sapiens |
2 | Acrolein increased hMMP9 transcripts in human airway cells, which was inhibited by an MMP inhibitor, EGFR-neutralizing antibody, or a mitogen-activated protein kinase (MAPK) 3/2 inhibitor. | Acrolein | matrix metallopeptidase 9 | Homo sapiens |