Pub. Date : 2008 Jan 18
PMID : 18006147
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. | Curcumin | ATP-binding cassette, sub-family B (MDR/TAP), member 1B | Mus musculus |
2 | Transfection with a series of 5"-deleted constructs of the mdr1b gene promoter indicated that a proximal region between -205 and +42 of the sequence was responsible for the suppression of promoter activity by curcumin. | Curcumin | ATP-binding cassette, sub-family B (MDR/TAP), member 1B | Mus musculus |