Title : Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway.

Pub. Date : 2008 Jan 18

PMID : 18006147






2 Functional Relationships(s)
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1 Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. Curcumin ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus
2 Transfection with a series of 5"-deleted constructs of the mdr1b gene promoter indicated that a proximal region between -205 and +42 of the sequence was responsible for the suppression of promoter activity by curcumin. Curcumin ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus