Title : Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells.

Pub. Date : 2008 Jan 11

PMID : 17996726






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mevastatin treatment transcriptionally and translationally up-regulated RhoA expression in the cells by negative feedback mechanism. mevastatin ras homolog family member A Homo sapiens
2 While TSA enhanced mevastatin-induced RhoA up-regulation, more importantly, it also accelerated mevastatin-mediated depletion of membrane-bound (geranylgeranylated) RhoA. mevastatin ras homolog family member A Homo sapiens
3 While TSA enhanced mevastatin-induced RhoA up-regulation, more importantly, it also accelerated mevastatin-mediated depletion of membrane-bound (geranylgeranylated) RhoA. mevastatin ras homolog family member A Homo sapiens