Title : 1,25-dihydroxyvitamin D3 and dexamethasone increase interleukin-10 production in CD4+ T cells from patients with Crohn's disease.

Pub. Date : 2007 Dec 15

PMID : 17996686






2 Functional Relationships(s)
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1 RESULTS: In T cells from CD patients, 1,25-dihydroxyvitamin D3 and DEX increased IL-10 production from a median of 0.08 ng/ml to 0.2 ng/ml (p<0.01) and downregulated IFN-gamma production from 8.3 ng/ml to 3.1 ng/ml (p<0.01). Dexamethasone interferon gamma Homo sapiens
2 CONCLUSION: We found that 1,25-dihydroxyvitamin D3 with and without DEX stimulation increased IL-10 and reduced IFN-gamma production. Dexamethasone interferon gamma Homo sapiens