Pub. Date : 2007 Dec
PMID : 17982670
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TPA also induced activation of ERK, p38 mitogen-activated protein kinase (MAPK), JNK, phosphatidylinositol-3-kinase (PI-3K), or nuclear factor (NF)-kappaB. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Pre-treatments with protein kinase C (PKC) inhibitors significantly inhibited TPA-induced expression of B7-DC, -H1, -H2, and -H3 mRNA as well as TPA-induced phosphorylation of ERK, p38 MAPK, JNK, and PI-3K. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Pre-treatments with protein kinase C (PKC) inhibitors significantly inhibited TPA-induced expression of B7-DC, -H1, -H2, and -H3 mRNA as well as TPA-induced phosphorylation of ERK, p38 MAPK, JNK, and PI-3K. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | Distinctly, the expression of B7-DC mRNA and -H3 mRNA in response to TPA is also PI-3K- and JNK-dependent, respectively. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 8 | Homo sapiens |