Title : Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue.

Pub. Date : 2008 Jun

PMID : 17950494






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The central part of the inhibitor binds in an improved melagatran-like mode, while the structure identifies a d-tyrosine as P1 residue which forms a charged hydrogen bond with Asp 189 of thrombin. Aspartic Acid coagulation factor II, thrombin Homo sapiens