Title : Effects of a selective cyclooxygenase-2 inhibitor on postoperative inflammatory reaction and pain after total knee replacement.

Pub. Date : 2008 Jan

PMID : 17950038






2 Functional Relationships(s)
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1 Rofecoxib significantly decreased regional IL-6 and TNF-alpha level after surgery. rofecoxib interleukin 6 Homo sapiens
2 Moreover, the incidence of febris and degree of local edema were lower in the rofecoxib group (P < .05), and peripheral IL-6 level significantly correlated with pain score at 48 hours. rofecoxib interleukin 6 Homo sapiens