Title : Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance.

Pub. Date : 2007 Oct 23

PMID : 17940018






1 Functional Relationships(s)
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1 To determine whether primary defects in mitochondrial beta-oxidation can cause insulin resistance, we studied mice with a deficiency of long-chain acyl-CoA dehydrogenase (LCAD), a key enzyme in mitochondrial fatty acid oxidation. Fatty Acids acyl-Coenzyme A dehydrogenase, long-chain Mus musculus