Pub. Date : 2007 Sep
PMID : 17929550
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: To investigate the effects of testosterone on extracellular signal-regulated kinase l/2 ( ERK1/2) phosphorylation in human umbilical vein endothelial cells (HUVEC). | Testosterone | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | METHODS: Activations of ERK1/2 stimulated by physiological testosterone were detected by Western blotting in cultured HUVEC. | Testosterone | mitogen-activated protein kinase 3 | Homo sapiens |
| 3 | RESULTS: A rapid phosphorylation expression of ERK1/2 was observed by treatment of the HUVECs with 3 x 10(-8) mol/L testosterone, especially at 30 minutes. | Testosterone | mitogen-activated protein kinase 3 | Homo sapiens |
| 4 | CONCLUSION: Testosterone at physiological concentrations induces the mitogen-activated protein kinase (MAPK, ERK1/2 and MEK1/2) phosphorylation within a short time, and flutamide could impair the process. | Testosterone | mitogen-activated protein kinase 3 | Homo sapiens |
| 5 | CONCLUSION: Testosterone at physiological concentrations induces the mitogen-activated protein kinase (MAPK, ERK1/2 and MEK1/2) phosphorylation within a short time, and flutamide could impair the process. | Testosterone | mitogen-activated protein kinase 3 | Homo sapiens |