Title : Synergistic effect of high glucose and ANG II on proliferation of mouse embryonic stem cells: involvement of PKC and MAPKs as well as AT1 receptor.

Pub. Date : 2008 May

PMID : 17929248






2 Functional Relationships(s)
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1 High glucose levels increase the level of PKC alpha, epsilon, and zeta translocation from the cytosol to the membrane fraction. Glucose protein kinase C, alpha Mus musculus
2 In conclusion, the combined treatment of a high glucose concentration and ANG II had a synergistic effect in stimulating mouse ES cell proliferation through the Ca2+/PKC, MAPKs, and the AT1 receptor. Glucose protein kinase C, alpha Mus musculus