Title : TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo.

Pub. Date : 2007 Nov 14

PMID : 17914460






1 Functional Relationships(s)
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1 Tdp1-/- mice treated with topotecan, a drug that increases levels of Top1-DNA complexes, also demonstrated significant loss of intestinal and hematopoietic progenitor cells. Topotecan tyrosyl-DNA phosphodiesterase 1 Mus musculus