PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17914460-6 2007 Tdp1-/- mice treated with topotecan, a drug that increases levels of Top1-DNA complexes, also demonstrated significant loss of intestinal and hematopoietic progenitor cells. Topotecan 26-35 tyrosyl-DNA phosphodiesterase 1 Mus musculus 0-4