Title : Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus.

Pub. Date : 2007 Oct 15

PMID : 17911642






3 Functional Relationships(s)
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Protein Name
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1 Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus. Hydralazine mitogen-activated protein kinase 1 Homo sapiens
2 T cells from patients with lupus or treated with the lupus-inducing drug hydralazine have defective ERK phosphorylation. Hydralazine mitogen-activated protein kinase 1 Homo sapiens
3 We therefore analyzed the PMA stimulated ERK pathway phosphorylation cascade in CD4(+) T cells from patients with lupus and in hydralazine-treated cells. Hydralazine mitogen-activated protein kinase 1 Homo sapiens