Title : Identification of regulatory elements in the Cyp19 proximal promoter in rat luteal cells.

Pub. Date : 2007 Oct

PMID : 17909262






2 Functional Relationships(s)
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1 The Cyp19 promoter contains a cAMP response element-like sequence (CLS), two nuclear receptor elements half sites (NREs), a GATA binding site, a Yin Yang-1 (YY1) response element, and an activation protein 3 (AP3) binding site. gata cytochrome P450, family 19, subfamily a, polypeptide 1 Rattus norvegicus
2 Our results indicate that CLS is active only in follicles; whereas in the CL, binding to the GATA, NRE, and AP3 sites associates with changes in Cyp19 expression, suggesting that they control Cyp19 promoter activity in luteal cells. gata cytochrome P450, family 19, subfamily a, polypeptide 1 Rattus norvegicus