Title : A shuffled CYP2C library with a high degree of structural integrity and functional versatility.

Pub. Date : 2007 Nov 15

PMID : 17904094






2 Functional Relationships(s)
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1 Turnover rates for luciferin ME and H metabolism by CYP2C9 and mutants were at least one order of magnitude higher in experiments with membranes compared to whole cells, consistent with impaired product egress from cells. D-luciferin cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 Finally screening with a panel of CYP2C ligands using CYP2C9 or active mutants revealed different patterns of inhibition and heteroactivation of metabolism of luciferin analogs. D-luciferin cytochrome P450 family 2 subfamily C member 9 Homo sapiens