Title : Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.

Pub. Date : 2007 Nov

PMID : 17890284






1 Functional Relationships(s)
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1 CONCLUSIONS: We provide evidence that lopinavir is a substrate of P-gp, MRP1 and MRP2. Lopinavir ATP binding cassette subfamily C member 1 Homo sapiens