Title : IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs.

Pub. Date : 2007 Sep 25

PMID : 17878297






1 Functional Relationships(s)
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1 Stimulation of both large and microvascular endothelial cells with IL-20 leads to activation of receptor-dependent multiple intracellular signaling components, including increased phosphorylation levels of JAK2/STAT5, Erk1/2, and Akt; activation of small GTP-binding proteins Rac and Rho; and intracellular release of calcium. Calcium Janus kinase 2 Rattus norvegicus