Pub. Date : 2007 Dec
PMID : 17876861
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Uptake of metformin was facilitated by over-expression of hOCT1 and hOCT2 and showed saturable processes, indicating that metformin is a substrate of hOCT1 and hOCT2. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 2 | Uptake of metformin was facilitated by over-expression of hOCT1 and hOCT2 and showed saturable processes, indicating that metformin is a substrate of hOCT1 and hOCT2. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 3 | Uptake of metformin was facilitated by over-expression of hOCT1 and hOCT2 and showed saturable processes, indicating that metformin is a substrate of hOCT1 and hOCT2. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 4 | Uptake of metformin was facilitated by over-expression of hOCT1 and hOCT2 and showed saturable processes, indicating that metformin is a substrate of hOCT1 and hOCT2. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 5 | The IC(50) values of TAAs for hOCT2 were lower than hOCT1 and decreased with increasing alkyl chain length, indicating that the inhibitory potential of TAAs on metformin uptake was greater in hOCT2 than in hOCT1 and increased with increasing alkyl chain length. | Metformin | solute carrier family 22 member 1 | Homo sapiens |